Treatment-Resistant OCD
The newest treatments for OCD
Obsessive-compulsive disorder (OCD) is a chronic and often debilitating condition that affects millions worldwide. It is characterized by intrusive, distressing thoughts (obsessions) and repetitive behaviors or mental acts (compulsions) performed to reduce anxiety.
For many, standard treatments like medication and therapy provide relief. But for up to one-third of individuals, symptoms persist despite these efforts. This is known as treatment-resistant OCD.
For up to one-third of individuals with OCD, symptoms persist despite medication and therapy.
What is treatment-resistant OCD?
Treatment-resistant OCD is typically diagnosed when a person does not respond to or tolerate at least two different medications combined with evidence-based therapy, such as Exposure and Response Prevention (ERP).
If you’ve tried multiple approaches without success, advanced interventional options may help.
How is OCD treated?
At Breakthru Psychiatric Solutions, Dr. Karen Giles collaborates with your primary psychiatrist, PCP, or psychologist to provide innovative, evidence-based treatments for OCD when traditional methods fall short.
Interventional therapies for OCD
We offer advanced options designed to target the brain circuits involved in OCD:
AMPLIFI TMS Protocol
Our most advanced treatment for OCD is AMPLIFI, a cutting-edge Transcranial Magnetic Stimulation (TMS) protocol. Unlike standard TMS, AMPLIFI combines dual-target stimulation, accelerated sessions, and medication augmentation for enhanced results.
Key features of AMPLIFI:
- Dual Brain Targets:
- Dorsomedial Prefrontal Cortex (DMPFC) – intermittent Theta Burst Stimulation (iTBS)
- Right Orbitofrontal Cortex (rOFC) – continuous Theta Burst Stimulation (cTBS)
- Accelerated Schedule:
- 20 sessions (split into two days of 10 treatments each)
- Sessions start every 30 minutes
- Medication Support:
- Lisdexamfetamine (20 mg) and D-cycloserine (125 mg) to boost treatment response
Rapid Results: Intensive protocol completed in days, not weeks
AMPLIFI is an advanced, off-label protocol based on evolving clinical research. While promising, it is currently not covered by insurance and is offered on a self-pay basis at Breakthru Psychiatric Solutions.
IV Ketamine Therapy
IV Ketamine is an anesthetic that also has a significant effect on OCD. Ketamine therapy involves having an intravenous (IV) line in your arm. The medication then drips steadily into your bloodstream over the next 50 minutes.
Let's connect to find out how you can overcome treatment-resistant OCD.
*All interventional treatments for anxiety and OCD are currently not covered by insurance and are cash-pay only.
*Breakthru does not provide medication management and offers the interventional therapies listed above in conjunction with the support of your primary psychiatrist or PCP.