Physician-led, interventional psychiatry experts
Spravato
Treatment for MDD
Targeted relief for treatment-resistant depression
For depression
By treatment 13, 89.7% of patients showed improvement, and 31.0% achieved remission.
Among those with severe depression, 59.1% improved to mild or better.
For anxiety
By treatment 13, 88.9% of patients showed improvement, and 18.5% achieved remission.
Among those with severe anxiety, 46.2% improved to mild or better
Spravato® is an esketamine nasal spray that has FDA approval for helping patients with treatment-resistant depression. Experienced psychiatrist Karen Giles, MD, MS, at Breakthru Psychiatric Solutions in Sandy Springs and Alpharetta, Georgia, specializes in using innovative therapies like Spravato and IV Ketamine infusions to treat long-term depression when nothing else is helping. To learn more about fast-acting Spravato treatments and how those treatments could benefit you, call Breakthru Psychiatric Solutions today or book an appointment online.
What is Spravato?
Spravato contains a refined form of IV Ketamine (called esketamine) that is delivered in the form of a nasal spray. It can help patients with depression (major depressive disorder) when other treatments aren’t working.
Breakthru Psychiatric Solutions specializes in treating depression, particularly in moderate to severe cases and in patients who have treatment-resistant depression (TRD). They offer Spravato as part of their range of innovative depression treatments.
Spravato is by prescription only, and you have to receive it from a psychiatrist. It has FDA approval for depression, which means your insurance may cover it.
How does Spravato work?
Typical antidepressants increase levels of naturally occurring chemicals in the brain, such as serotonin, norepinephrine, and dopamine. These chemicals are messengers that allow brain cells to communicate, and in people with depression, these chemicals are typically altered. The scientific understanding is that increasing these chemicals (called neurotransmitters) allows for better communication between brain cells, positively affects mood, and alleviates depression symptoms.
Spravato builds off of this same science but delivers a greater impact in a shorter amount of time for many of the people for whom traditional antidepressants haven’t worked. Spravato increases levels of glutamate, the most abundant chemical messenger in the brain. The result of this is a greater impact on more brain cells at one time.
Spravato immediately impacts brain cells, offering relief from depressive symptoms within hours rather than several weeks from traditional antidepressants.
Why would I need to use Spravato?
- Treatment-resistant depression:
Dr. Giles may recommend Spravato if you’ve been treated for major depressive disorder but haven’t experienced significant improvement. - Limited response to traditional treatments:
While psychotherapy and antidepressant medications help many people, studies show that 30–40% of patients do not find adequate relief from these methods. - Targeted relief:
Spravato is designed to address treatment-resistant depression, providing an alternative for individuals who haven’t responded to standard approaches. - Personalized treatment options:
Breakthru Psychiatric Solutions also offers IV (intravenous) Ketamine therapy.
Dr. Giles will discuss both Spravato and IV Ketamine options with you to determine which treatment best fits your needs.
What’s involved in Spravato treatment?
Spravato treatment is very straightforward. You need to visit Breakthru Psychiatric Solutions for each treatment, as you must have it under Dr. Giles’ supervision. The treatment itself simply involves administering the spray into your nasal passages.
The FDA-approved protocol for Spravato is twice-weekly treatments for 4 weeks, and then once a week for 4 weeks. Breakthru highly recommends a taper protocol following the FDA-approved protocol to support ongoing remission.
If you’d like to find out more about treating persistent depression with Spravato, call Breakthru Psychiatric Solutions today or book an appointment online.
Why choose Breakthru?
Schedule your consultation today to learn more about Spravato.
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Frequently asked questions
Is Spravato covered by insurance?
Yes, Spravato is covered by insurance with prior authorization by your insurance company.
How quickly will I see results from Spravato treatment?
Most patients report a noticeable response after 3 – 8 treatments, and may achieve remission by 12 treatments. Please remember that everyone’s journey is different.
How often will I need to come to the office for this treatment?
The FDA-approved protocol for Spravato is twice-weekly treatments for 4 weeks, and then once a week for 4 weeks. Breakthru highly recommends a taper protocol and maintenance treatments following the FDA-approved protocol to support ongoing remission. The FDA-approved protocol is 12 treatments, provided you tolerate the medication.